After entering the digestive system, the drug is quickly absorbed and begins to act
For instance, MPTPs selective destruction of dopaminergic neurons via mitochondrial complex I inhibition is a well-documented cause of drug-induced parkinsonism
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Denis, Effects of N-acetylcysteine, oral glutathione (GSH) and a novel sublingual form of GSH on oxidative stress markers: A comparative crossover study., Redox Biology, Volume 6, 2015, Pages 198-205, ISSN 2213-2317
However, oral glutathione can break down in the digestive system before reaching the bloodstream
It works best when injected directly at the injury site