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Any real decision to change dose on an investigational drug belongs with a licensed clinician, not a troubleshooting checklist

epigenetic aging was not pre-specified

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[28] The medication may reduce neutrophil migration to inflammatory sites and could inhibit the release of inflammatory mediators from these cells

Despite these limitations, our results suggest that supercooled RBCs stored at -4 C in E-Sol5 represent a good compromise between a sufficiently slower metabolism that preserves both energy and antioxidant reservoirs, without inducing excess hemolysis observed at -8 C