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At 0.5mm, at-home microinfusion will produce surface texture improvement and may modestly soften the appearance of shallow scars over months, but will not deliver the deeper dermal remodeling that improves the morphology of boxcar, rolling, or ice-pick scars

AOD 9604 efficacy in clinical trials was modest at best

Wash After incubation, unbound proteins and non-specifically bound proteins need to be removed by washing steps

The Purity Gamble: This is the biggest one

Metabolic adaptations from MOTS-c and 5-Amino-1MQincreased mitochondrial density, improved insulin sensitivity, enhanced fat oxidation capacitypersist for 48 weeks after discontinuation before gradually regressing toward baseline

During the Q&A session, Frias was asked whether he was surprised about the safety profile from the trial, as no participants in the combination group withdrew due to adverse events