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DPP-4 inhibitors may be a treatment option for patients in whom metformin is contraindicated due to decreased renal function or intolerable gastrointestinal side effects

You develop allodynia accompanied by vision changes, balance problems, or difficulty speaking

While paraxanthine delivers most of caffeine's beneficial effects with a relatively short half-life of 3.1 hours, the other two metabolites are more problematic

Other notable adverse effects include injection site reactions (redness, itching, or swelling), fatigue, and dizziness

Aberrations in folate metabolic pathway and altered susceptibility to autism

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