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Filing method-of-use patents tied to specific patient subpopulations, biomarker-defined indications, or combination regimens creates a layered IP estate that complicates any Paragraph IV challenge and preserves PBM negotiating leverage throughout the exclusivity lifecycle

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Its unfortunate that theyre excluding a whole class of medications that seem to have a tremendous number of health benefits to patients, Dr

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[DOI] [PubMed] [Google Scholar] 45.Deserno M.K., Bathelt J., Groenman A.P., Geurts H.M