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J Clin Endocrinol Metab (2010) 95(5):211322

Cognitive Impairment Models: Dihexa has been tested in scopolamine-induced amnesia models and aged rat models, where it demonstrated restoration of cognitive performance on spatial memory tasks

Exposure to 40C or above can destroy the peptide within hours

The study then confirmed that depleting gut bacteria via antibiotics or germ-free mouse models essentially abolishes postprandial GLP-1, while fecal microbiota transplantation (FMT) restores it

The 15-amino-acid sequence subsequently designated BPC-157 was defined from that work

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