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The study that was published in 2007 in the Journal of Dermatological Science was in this respect exceptional although it wasn't strictly speaking a true study, but a Letter to the Editor

This matters because insulin resistance impairs hormone-sensitive lipase (HSL), the enzyme that liberates fatty acids from triglyceride stores in fat cells

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doi: 10.1016/j.brainres.2006.06.042

(234), who analyzed autophagy pathways in HT-29, SW48 and Caco-2 cells and showed that MEL increased CRC death, oxidative stress and autophagic vacuole formation in a dose-dependent manner