Trial figures represent group averages in specific populations and do not predict individual outcomes
Any consideration of combined use should only occur under specialist supervision (endocrinologist or metabolic physician) within a formal clinical trial or with robust multidisciplinary oversight
Scott Butsch, director of obesity medicine at the Cleveland Clinic Bariatric and Metabolic Institute
And, as one might expect from the no-bulls--t host of podcast Keeping It Real , she didn't hold back when asked about her apprehension toward the semiglutide injectable used by stars like Sharon Osbourne (who has since said she's struggled to put weight back on) and Chelsea Handler , who said she didn't like how it made her feel
both are advanced compounds with substantial trial data
Efficacy: Both Ozempic and other GLP-1 medications have been shown to help with weight loss, but some studies suggest that newer GLP-1 drugs may have slightly greater effects on weight reduction