The same medication that some users blame for their insomnia has been clinically proven to treat one of the most common sleep disorders
In cirrhotic patients peripheral blood mononuclear cells and gastric cancer cell lines, palmitoylcarnitine (C16:0) has been shown to directly integrate into the mitochondrial membrane, inducing membrane potential collapse, ROS production, and cytochrome c release, ultimately activating caspase-mediated apoptosis [124, 125]
*Correspondence: Ruijin Wu, [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Reproduction, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
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While gastrointestinal side effects are common with this medication class, blood in the stool is not listed as a typical adverse effect in the FDA prescribing information for either Mounjaro or Zepbound