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Genetic insights allow clinicians to anticipate vulnerable individuals and adjust dosing, combination protocols, or concurrent support strategies

Indeed, in the cardiovascular outcome trial (CVOT) for semaglutide, SUSTAIN 6 a relatively short (two-year) and small (3,297 individuals) preregistration trial (an extensive CVOT in obese individuals without T2DM (SELECT) is expected to complete in 2024) HbA 1c was powerfully and durably reduced

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**Factors Influencing the Timeline:** * **Individual Response:** People metabolize and respond to medications differently