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Antidepressant use in IBS is associated with a higher risk of all-cause mortality across subclasses and patient subgroups, whereas antispasmodics are not associated with increased mortality

Anti-inflammatory action

Nielsen, J

Renal tubule CPT1A overexpression protects from kidney fibrosis by restoring mitochondrial homeostasis

This often leaves the patient or the healthcare provider responsible for the full cost of the treatment, as most insurers will not grant retroactive authorization except in very specific emergency circumstances

Limitations of the TRIUMPH-1 results The results of TRIUMPH-1 have only come through a press release, not the publication of a peer-reviewed journal