DESIGNED TO BE Reusable for environmental stewardship Ready for the connected world Powerful and flexible platform for pharma Small and easy to use A Reusable Autoinjector with a Disposable Cassette DESIGNED WITH INTELLIGENT, REUSABLE DRIVE UNIT WITH OPTIMAL CONNECTIVITY Powerful motor to drive controlled injection of low- and high-viscosity liquid drugs (1 to 200 cps*) Full dose delivery in 10 seconds (adjustable) Simple sleeve-triggered/push-action operation Visual and audible user feedback Rechargeable with 3-year service life (i.e., up to 3 x 365 uses) Optional built-in Bluetooth low energy (BLE) connectivity SINGLE-USE DISPOSABLE CASSETTE 1 ml and 2.25 ml prefilled syringes (glass or COP) with RNS Standard subcutaneous delivery Needle safety before/after injection Up to 70 percent less CO2e impact than disposable autoinjectors Large inspection window Optional radio frequency identification (RFID) Technical Specifications Data provided for standard models

P values were derived from two-sided Pearsons chi-square tests ( b ), One-way ANOVA ( c,f,h ), two-sided unpaired t-test ( g )
For this purpose, we utilized 4-hydroxy-2-nonenal (4-HNE), which is one of the major products of lipid peroxidation and can be used as a marker for oxidative stress 11,12,13
Regulating insulin secretion by increasing insulin secretion from the pancreas in a glucose-dependent manner and increasing insulin-sensitivity in both alpha and beta cells Regulating glucagon secretion by decreasing glucagon secretion from the pancreas by engagement of a specific G protein-coupled receptor
The reconstituted peptide is stable for several weeks when refrigerated
Improved Muscle Mass By stimulating the secretion of growth hormones, CJC injections can enhance your lean muscle mass