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In the study of etinkaya et al ., they stated that n-acetylcysteine decreased LPO in the liver tissue and increased GSH level and SOD activity in the MTX-induced oxidative stress (Reference Cetinkaya, Kurutas and Bulbuloglu46)

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Moreover, HGF overexpression attenuates monocyte chemoattractant protein-1 (MCP-1) induction, predominantly in astrocytes, thus reducing accumulation of activated microglia (Kadoyama et al., 2007)

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