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Chronic niacin deficiency leads to pellagra, a condition now rare in developed countries due to its association with poor nutrition, resulting from low intake of niacin or tryptophan (54)

KPV has been studied in intestinal inflammation because the gut lining contains epithelial cells and immune cells that participate in inflammatory signaling

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10.1002/adhm.202100683 Summary Keywords system Xc -/GSH/GPX4 axis, ferroptosis, drug resistance, solid tumor, therapy Citation Li F-J, Long H-Z, Zhou Z-W, Luo H-Y, Xu S-G and Gao L-C (2022) System X c /GSH/GPX4 axis : An important antioxidant system for the ferroptosis in drug-resistant solid tumor therapy

Description Overview Epithalon (also known as Epitalon) is a synthetic research peptide consisting of four amino acids (Ala-Glu-Asp-Gly) that corresponds to the active fragment of epithalamina polypeptide originally isolated from the pineal gland