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GLP-1 Podcast with Flow Wellness Medical Director Key takeaways from the GLP-1 podcast GLP-1 medications were first developed for diabetes, then became widely used for weight loss after weekly dosing became available
As the gut adjusts, symptoms typically resolve
Recent systemic review and meta-analysis demonstrated, that treatment with functional agonists of GLP-1 which included both GLP-1RAs and DPP4 inhibitors resulted in a significant reduction of depression rating scores and tended to be superior over control treatments, which supports the hypothesis of their antidepressant action in humans
Constipation becomes a real issue, and if fiber intake drops alongside appetite, it compounds the problem significantly
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A single early dose does not accelerate weight loss or improve blood sugar control
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