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In our model, the dynamics of this exchanger are captured using a linear exchange model as outlined by Keener and Sneyd (2009) (see Supplementary Material S \)C labelling experiment

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-MSH binding to MC1R results in the activation of adenylyl cyclase, increasing the intracellular levels of cAMP and subsequently upregulating TYR, tyrosinase related protein-1 (TRP-1) and tyrosinase related protein-2 (TRP-2) expression

(3) Gut microbiota modulation Phospholipids in fish increase gut Akkermansia muciniphila abundance, promoting SCFA production

Research supports: Reduced joint inflammation in arthritis models with daily use, showing long-term benefits up to one year

Peptides support but do not replace appropriate medical evaluation