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Rarely, and almost exclusively from injections rather than oral supplements

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"If someone injects it under their skin, what are they getting?" During the COVID-19 pandemic, the FDA issued over a half-dozen warning letters to businesses promoting peptides with "immune-boosting powers." Then in 2023, the agency added nearly 20 peptides to a list of substances that should not be compounded due to safety risks

Well, the consensus leans towards peptides first