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The effect of GLP- 1 together with GIP on food intake, body weight, and locomotor activity was determined following intracerebroventricular (ICV) administration of GLP- 1 and/or GIP in mice

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Glucagon-like peptide-1 (GLP1) regulates blood sugar and appetite Glucose-dependent insulinotropic polypeptide (GIP) regulates insulin Glucagon controls blood sugar levels Together, these multiple pathways are all involved in appetite, satiety and digestive speed