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Body weight, waist circumference and vital signs (systolic and diastolic blood pressure and pulse) were measured at baseline

Cagrilintide is a long-acting amylin analogue with dual amylin and calcitonin receptor activity, whereas semaglutide is a once-weekly GLP-1 receptor agonist with robust anti-hyperglycemic and appetite-suppressing effects

Histological analysis revealed widespread, intensive A42 staining in neurons of the cortex and hippocampus at 12 months, though no amyloid plaques were detected (Hwang et al., 2004)

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