Such a robust fibrosis can be induced in rodents with prolonged or repeated exposure to certain chemicals (carbon tetrachloride, alcohol, tetrachlorovinphos, diallylphthalate), dietary lipotrope deficiency, or chronic hepatitis secondary to persistent infection (Ward 1997)
The foundational characterization appeared in European Journal of Endocrinology in 1998, reporting selective agonism of the growth hormone secretagogue receptor type 1a (GHS-R1a) without significant elevation of ACTH, cortisol, prolactin, FSH, LH, or TSH, even at doses 200-fold above the GH-releasing ED50 in preclinical models
Taking the advised doses regularly has been shown to exhibit effective and optimal effects
Deboned chicken, chicken meal, lentils, peas, oatmeal, pearled barley, natural chicken flavor, chicken fat (preserved with mixed tocopherols and citric acid), freeze-dried chicken, sun-cured alfalfa meal, pea protein, choline chloride, pea fiber, potassium chloride, fish oil, taurine, yeast extract, salt, inulin, zinc proteinate, L-lysine, DL-methionine, freeze-dried sweet potatoes, apples, blueberries, carrots, cranberries, pumpkin, ground ginger, vitamin E supplement, iron proteinate, freeze-dried pumpkin, L-carnitine, L-ascorbyl-2-phosphate (source of vitamin C), niacin supplement, Yucca schidigera extract, freeze-dried cod liver, freeze-dried New Zealand green lipped mussel, freeze-dried kelp, d-calcium pantothenate, manganese proteinate, sunflower oil, dried Bifidobacterium bifidum fermentation product, dried Enterococcus faecium fermentation product, dried Lactobacillus acidophilus fermentation product, dried Lactobacillus casei fermentation product, riboflavin supplement, vitamin A supplement, copper proteinate, thiamine mononitrate, vitamin B12 supplement, menadione sodium bisulfite complex, pyridoxine hydrochloride, biotin, canola oil, sodium selenite, vitamin D3 supplement, folic acid, calcium iodate, rosemary extract
Retrospective studies are inconsistent
Also supports healthy lung function
